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KMID : 0377619700180010029
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Korean Jungang Medical Journal
1970 Volume.18 No. 1 p.29 ~ p.32
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Anticonvulsant Effect of Panax Ginseng on Mice
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李惠子/Lee, Hai Ja
具姬洙/孔化淳/申萬鍊/Koo, Hee Soo/Kong, Wha Shun/Shin, Man Ryun
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Abstract
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It has been reported that the convulsion induced by cocain was suppressed by Panax Ginseng and the onset of convulsion by metrazol and picrotoxin on frogs was definitely prolonged in large doses of Panax Ginseng.
In this study, it was attempted to investigate the anticonvulsant effect of Panax Ginseng extract on the cardiazol convulsion of mice. And the anticonvulsant effect of Panax Ginseng ,extract was compared with pheny tion and reserpine on the cardiazol convulsion.
The following results were obtained.
1. The onset of the cardiazol convulsion on mice was definitely prolonged by pretreatment
with Panax Ginseng extract for both 7 days and 15 days.
2. The prolongation of the onset of the cardiazol convulsion by Panax Ginseng extract was
almost same as phenytoin 1mg/kg.
3. The onset of the cardiazol convulsion on mice was inclined to shorten by the pretreatment with reserpine.
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